Hypercholesterolemia is characterized by high plasma LDL cholesterol and often caused by genetic mutations in LDL receptor (LDLR), APOB, or Vitamin B-12 proprotein convertase subtilisin/kexin type 9 (PCSK9).However, a substantial proportion of hypercholesterolemic subjects do not have any mutations in these canonical genes, leaving the underlying p
Background and Aims: Current prediction models for early recurrence of hepatocellular carcinoma (HCC) after surgical resection remain unsatisfactory.The aim of this study was to develop evolutionary learning-derived prediction models with interpretability using both clinical and radiomic features to predict early recurrence of HCC after surgical re
Michaël Benzimra,1 Béatrix Bonnamour,1 Martin Duracinsky,2 Christophe Lalanne,2 Jean-Pierre Aubert,2,3 Olivier Chassany,2,3 Isabelle Aubin-Auger,2,3 Isabelle Mahé1,2 1Internal Medicine Department, Hôpital Louis Mourier, APHP, Colombes, France; 2Méthodologies et Société (REMES) EA 7334, Recherche Cliniqu
It is critical to develop a fast Security and simple method to remove air bubbles inside microchannels for automated, reliable, and reproducible microfluidic devices.As an active degassing method, this study introduces a lateral degassing method that can be easily implemented in disposable film-chip microfluidic devices.This method uses a disposabl
Balanced chromosome translocations carriers mostly Sweater do not have recognizable phenotypic expression but may have more risk of recurrent spontaneous abortions &/or children with serious birth defects due to unbalanced chromosome complements.Unbalanced chromosomal rearrangements have variable clinical expression and are rare.We present here a c